Multiple marker second trimester serum screening for pre-eclampsia
نویسندگان
چکیده
منابع مشابه
Second-trimester uterine artery Doppler pulsatility index and maternal serum PP13 as markers of pre-eclampsia.
OBJECTIVE To evaluate whether measurement of maternal serum PP13 at 22 to 24 weeks of gestation, alone or in combination with second-trimester biochemical markers or uterine artery pulsatility measured by Doppler velocimetry, is useful in predicting those women at risk of developing pre-eclampsia. STUDY DESIGN A nested case-control study of pre-eclampsia cases with controls matched for gestat...
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BACKGROUND ADAM 12 is a placenta-derived glycoprotein that is involved in growth and differentiation. The maternal serum concentration of ADAM 12 is a potential first-trimester maternal serum marker of Down syndrome (DS). Here we examine the potential of ADAM 12 as a second-trimester maternal serum marker of DS. MATERIALS AND METHODS The concentration of ADAM 12 was determined in gestational ...
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The aim of this study was to evaluate the additional value of dimeric inhibin-A serum concentration in second trimester multiple-marker screening tests for pregnancies affected by Down's syndrome. We anticipated that second trimester maternal serum dimeric inhibin-A concentrations would be altered in pregnancies complicated by fetal Down's syndrome and that dimeric inhibin-A would perform bette...
متن کاملA novel approach to first-trimester screening for early pre-eclampsia combining serum PP-13 and Doppler ultrasound.
OBJECTIVE To investigate the value of maternal serum placental protein 13 (PP-13) measurement and uterine artery Doppler during first-trimester screening in the prediction of early pre-eclampsia. METHODS This was a nested case-control prospective study of pregnancies at 11 + 0 to 13 + 6 weeks of gestation. The pulsatility index (PI) of blood flow in the uterine arteries and the maternal serum...
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ژورنال
عنوان ژورنال: Journal of Medical Screening
سال: 2001
ISSN: 0969-1413,1475-5793
DOI: 10.1136/jms.8.2.65